Mapping and characterization of the origin of DNA replication of porcine circovirus.

نویسندگان

  • A Mankertz
  • F Persson
  • J Mankertz
  • G Blaess
  • H J Buhk
چکیده

The origin of DNA replication of porcine circovirus (PCV) was mapped to a 111-bp fragment. On top of a hairpin, a nonanucleotide (TAGTATTAC) homologous to nonanucleotides of other viruses was identified. Mutation of this element abolishes replication. PCV may be related to a virus family characterized by single-stranded circular DNA genomes, rolling-circle replication, and homology of their rep proteins.

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Functional analysis of cis- and trans-acting replication factors of porcine circovirus type 1.

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عنوان ژورنال:
  • Journal of virology

دوره 71 3  شماره 

صفحات  -

تاریخ انتشار 1997